| Bioactivity | ATP-13C10,15N5 (disodium) is a 13C-labeled and 15N-labeled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation[1][2][3][4]. |
| Invitro | ATP-13C10,15N5 (Adenosine 5'-triphosphate-13C10,15N5; 5 mM; 1 hour) disodium co-treatment with LPS (1 μg/mL) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs[3].ATP-13C10,15N5 (2 mM; 0.5-24 hours) disodium induces secretion of IL-1β, KC and MIP-2 from BMDMs in a caspase-1 activation-dependent manner[4].ATP-13C10,15N5 disodium promotes neutrophil chemotaxis in vitro[4]. |
| Name | ATP-13C10,15N5 (disodium) |
| Formula | 13C10H1615N5Na2O13P3 |
| Molar Mass | 568.05 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Solution, -20°C, 2 years |
ATP-13C10,15N5 (disodium)
CAS: F: 13C10H1615N5Na2O13P3 W: 568.05
ATP-13C10,15N5 (disodium) is a 13C-labeled and 15N-labeled ATP (HY-B2176). ATP is a central component of energy storage
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