PeptideDB

AIE-Cbz-LD-C7

CAS: 2810130-33-5 F: C35H34N4 W: 510.67

AIECbz-LD-C7 is an aggregation-induced emission (AIE) probe based on the conjugation of quinoline-malononitrile (QM) and
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Bioactivity AIECbz-LD-C7 is an aggregation-induced emission (AIE) probe based on the conjugation of quinoline-malononitrile (QM) and carbazole. AIECbz-LD-C7 has excellent LD-specificity. AIECbz-LD-C7 can be used for tracking the dynamic changes of LDs and studying the association between LDs and lysosome/endoplasmic reticulum (ER)[1].
Invitro AIE-Cbz-LD-C (0, 2, 5, 10, 20, and 30 μM; 24 h) have excellent biocompatibility[1].AIECbz-LD-C7 (0.5 μM, 15 min) could aggregate in LDs accurately and light up the LDs with good photostability[1].AIE-Cbz-LD-C7 (0.5 μM) can be used to visualize the interplay between LDs and lysosomes during lipophag due to the excellent LD-specificity[1].AIE-Cbz-LD-C7 (0.5 μM, 15 min) increases the number of ferroptosis[1]. Cell Cytotoxicity Assay[1] Cell Line:
Name AIE-Cbz-LD-C7
CAS 2810130-33-5
Formula C35H34N4
Molar Mass 510.67
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Rui Chen, et al. Rational Design of Novel Lipophilic Aggregation-Induced Emission Probes for Revealing the Dynamics of Lipid Droplets during Lipophagy and Ferroptosis. Anal Chem. 2022 Sep 19.