| Bioactivity | A-61603 free base is a potent adrenergic receptor agonist. A-61603 free base reduces carotid artery conductance in anesthetized pigs mediated by α1 and α2 adrenergic receptors (pEC50=7.25). A-61603 free base can be used as a probe to study adrenergic function[1][2]. |
| CAS | 750531-54-5 |
| Formula | C14H19N3O3S |
| Molar Mass | 309.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Knepper S M, et al. A-61603, a potent alpha 1-adrenergic receptor agonist, selective for the alpha 1A receptor subtype[J]. Journal of Pharmacology and Experimental Therapeutics, 1995, 274(1): 97-103. [2]. Mehrotra S, et al. A61603‐Induced Contractions of the Porcine Meningeal Artery Are Mediated by α1‐and α2‐Adrenoceptors[J]. Basic & clinical pharmacology & toxicology, 2007, 100(4): 279-285. |
A-61603 (free base）
CAS: 750531-54-5 F: C14H19N3O3S W: 309.38
A-61603 free base is a potent adrenergic receptor agonist. A-61603 free base reduces carotid artery conductance in anest
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