| Bioactivity | 6-TRITC (Tetramethylrhodamine-6-isothiocyanate) is a potent fluorescent tracer. 6-TRITC can be used as an probe for haptenated proteins/peptides for the research of contact allergy. 6-TRITC can be used as a tracer for the confocal imaging in living cells[1][2]. |
| Invitro | 6-TRITC is relatively photostable and robust toward pH changes[1].6-TRITC as an extreme sensitizer induces a massive cell proliferation and gave an EC3 value of 0.92 mM (0.040%) in the murine LLNA (local lymph node assay)[1].6-TRITC (1.0 mg; 2h) can used as fluorescence probe for confocal imaging in Fe3O4@PDA incubated living cells[2]. |
| Name | 6-TRITC |
| CAS | 80724-20-5 |
| Formula | C25H21N3O3S |
| Molar Mass | 443.52 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Karlsson I, et al. Peptide Reactivity of Isothiocyanates--Implications for Skin Allergy. Sci Rep. 2016 Feb 17;6:21203. [2]. Yue Q ,et al . A versatile ethanol-mediated polymerization of dopamine for efficient surface modification and the construction of functional core-shell nanostructures. J Mater Chem B. 2013 Nov 28;1(44):6085-6093. |