| Bioactivity | 5-Valine-angiotensin I is an Ang I peptide belonging to angiotensin I. 5-Valine-angiotensin I induces muscle contraction, can be used for renin-angiotensin system studies. Angiotensin I is a putative neurotransmitter, is the precursor of angiotensin II and of angiotensin fragment 1-7, which are involved in regulation of fluid volume and the release of aldosterone[1][2]. |
| Invitro | 5-Valine-angiotensin I shows myotropic effect (muscle contraction) on isolated rat colon after nonspecific desensitization of receptors with acetylcholine[2]. |
| Name | 5-Valine-angiotensin I |
| CAS | 484-43-5 |
| Shortening | DRVYVHPFHL |
| Formula | C61H87N17O14 |
| Molar Mass | 1282.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hayashi Y, et al. Synthesis and specific pressor activity of [1-aspartic acid,5-valine,9-serine]angiotensin I ("fowl angiotensin I"). J Med Chem. 1977 Feb;20(2):315-6. [2]. Myshlyakova, et al. Pharmacological characteristics of "active sites" of the angiotensin. Khimiko-Farmatsevticheskii Zhurnal, 1977, 11(7):6-11. [Russian] |
5-Valine-angiotensin I
CAS: 484-43-5 F: C61H87N17O14 W: 1282.45
5-Valine-angiotensin I is an Ang I peptide belonging to angiotensin I. 5-Valine-angiotensin I induces muscle contraction
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