| Bioactivity | 5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells[1]. |
| Name | 5,7-Dihydroxychromone |
| CAS | 31721-94-5 |
| Formula | C9H6O4 |
| Molar Mass | 178.14 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Kim DW, et al. Neuroprotection against 6-OHDA-induced oxidative stress and apoptosis in SH-SY5Y cells by 5,7-Dihydroxychromone: Activation of the Nrf2/ARE pathway. Life Sci. 2015 Jun 1;130:25-30. |
5,7-Dihydroxychromone
CAS: 31721-94-5 F: C9H6O4 W: 178.14
5,7-Dihydroxychromone,the extract ofCudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects
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