| Bioactivity | 4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1[1]. | ||||||||||||
| Target | Nrf2 | ||||||||||||
| In Vivo | 4-Octyl Itaconate (OI) is a cell-permeable itaconate derivative. 4-Octyl Itaconate is protective against lipopolysaccharide-induced lethality in vivo and decreases cytokine production[1]. | ||||||||||||
| Name | 4-Octyl Itaconate | ||||||||||||
| CAS | 3133-16-2 | ||||||||||||
| Formula | C13H22O4 | ||||||||||||
| Molar Mass | 242.31 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117. |
4-Octyl Itaconate
CAS: 3133-16-2 F: C13H22O4 W: 242.31
4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates
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