4-Epianhydrotetracycline hydrochloride_product_DataBase

Bioactivity	4-Epianhydrotetracycline hydrochloride is a major intermediate product of Tetracycline (HY-A0107). 4-Epianhydrotetracycline hydrochloride shows lethal effects and induces cell apoptosis of zebrafish embryos. 4-Epianhydrotetracycline hydrochloride inhibits Shewanella, E. coli and P. aeruginosa with MIC values of 2, 1 and 64 mg/L, respectively[1].
Invitro	4-Epianhydrotetracycline hydrochloride (0-20 mg/L;96 h) 显著提高 ROS 水平、丙二醛 (MDA) 浓度和蛋白羰基 (PC) 含量，在 5-20.0 mg/L 的浓度区间[1]。4-Epianhydrotetracycline hydrochloride (0-20 mg/L;96 h) 剂量依赖性地影响 SOD 活性，呈先升高后降低的趋势，在 2.50 mg/L 剂量时，SOD 活性达到最大值[1]。4-Epianhydrotetracycline hydrochloride (0-20 mg/L;96 h) 诱导细胞凋亡[1]。4-Epianhydrotetracycline hydrochloride (0-100 mg/L) 对斑马鱼胚胎有致死作用，96 h 的 LC50 值为 29.13 mg/L[2]。4-Epianhydrotetracycline hydrochloride 增加斑马鱼胚胎畸形，96 h 的 EC50值为 8.57 mg/L[2]。4-Epianhydrotetracycline hydrochloride 抑制心率 (10-20 mg/L)，并表现出延迟孵化效应 (5-20.0 mg/L)[2]。4-Epianhydrotetracycline hydrochloride (0-20 mg/L) 抑制希瓦式菌属，大肠杆菌和绿脓杆菌的 MIC 值分别为 2、1 和 64 mg/L[3]。 Apoptosis Analysis[1] Cell Line:
Name	4-Epianhydrotetracycline hydrochloride
CAS	4465-65-0
Formula	C22H23ClN2O7
Molar Mass	462.88
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

PeptideDB

4-Epianhydrotetracycline hydrochloride

CAS: 4465-65-0 F: C22H23ClN2O7 W: 462.88