3-(Cyclohexylamino)-1-propanesulfonic Acid-d17_product_DataBase

Bioactivity	3-(Cyclohexylamino)-1-propanesulfonic Acid-d17 is the deuterium labeled CAPS[1]. CAPS, cyclohexylaminopropane sulfonic acid, is a surfactant. CAPS can be used as biological buffer (0.05 M, pH 11) for dialysis[2][3].
Invitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
Name	3-(Cyclohexylamino)-1-propanesulfonic Acid-d17
CAS	1219804-15-5
Formula	C9H2D17NO3S
Molar Mass	238.42
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Bedard P R, et al. Ion Interaction: The Energetics and Mechanism of The Competitive Behavior Between Two Similarly Charged Molecules. 1. The Effect of Ionic Strength, Acetonitrile and Surfactant Concentration[J]. Journal of Liquid Chromatography, 1985, 8(13):2417-2443. [3]. Oberley TD, et al. The effect of the dimeric and multimeric forms of fibronectin on the adhesion and growth of primary glomerular cells. Exp Cell Res. 1983 May145(2):265-76.

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