| Bioactivity | 2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate), an adenosine derivative, is a weak competitive inhibitor of ATP, with a Ki of 2.3 mM. 2'-NH2-ATP can be used in nucleic acid labeling[1][2][3]. |
| Invitro | 2'-NH2-ATP (2 mM) did not replace ATP as a substrate for NH3-dependent cytidine 5'-triphosphate (CTP) formation catalyzed by CTP synthase[2]. |
| Name | 2'-NH2-ATP |
| CAS | 61468-88-0 |
| Formula | C10H17N6O12P3 |
| Molar Mass | 506.20 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Armstrong VW, et, al. Interaction of substrate analogues with Escherichia coli DNA-dependent RNA polymerase. Eur J Biochem. 1976 Nov 1;70(1):33-8. [2]. Faylene A. L. KINETIC STUDIES ON WILD-TYPE AND MUTANT ESCHERICHIA COLICYTIDINE 5'-TRIPHOSPHATE SYNTHASES AND INHIBITOR DEVELOPMENT. Dalhousie University Halifax, Nova Scotia. 2008 Jul. [3]. Aström H, et, al. Acidity of secondary hydroxyls in ATP and adenosine analogues and the question of a 2',3'-hydrogen bond in ribonucleosides. J Am Chem Soc. 2004 Nov 17;126(45):14710-1. |
2'-NH2-ATP
CAS: 61468-88-0 F: C10H17N6O12P3 W: 506.20
2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate), an adenosine derivative, is a weak competitive inhibitor of ATP
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.