2-Chloroadenosine_product_DataBase

CAS: 146-77-0 F: C10H12ClN5O4 W: 301.69

2-Chloroadenosine, a stable adenosine analogue, protects against long term development of ischaemic cell loss in the rat

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

2-Chloroadenosine, a stable adenosine analogue, protects against long term development of ischaemic cell loss in the rat hippocampus. 2-Chloroadenosine is an apparent competitive inhibitor of uridine influx (apparent Ki=33 μM) and high-affinity nitrobenzylthioinosine binding (apparent Ki=0.18 mM). 2-Chloroadenosine is a transported permeant for the nucleoside transporter in human erythrocytes[1][2].

Name

2-Chloroadenosine

CAS

146-77-0

Formula

C10H12ClN5O4

Molar Mass

301.69

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reference

[1]. Jarvis SM,2-Chloroadenosine, a permeant for the nucleoside transporter.Biochem Pharmacol. 1985 Sep 15;34(18):3237-41. [2]. Evans MC, et al. An adenosine analogue, 2-chloroadenosine, protects against long term development of ischaemic cell loss in the rat hippocampus.Neurosci Lett. 1987 Dec 29;83(3):287-92.

PeptideDB

2-Chloroadenosine

CAS: 146-77-0 F: C10H12ClN5O4 W: 301.69