Bioactivity | (Thr4,Gly7)-Oxytocin, an Oxytocin analogue, is a specific OT receptor agonist. (Thr4,Gly7)-Oxytocin also excites subicular neurons via activation of TRPV1 channels, and depression of K+ channels. [1][2]. | ||||||
Invitro | (Thr4,Gly7)-Oxytocin (1 μM, 1 min) evokes an inward current of 5.9 pA in paraventricular thalamus (PVT) neurons[1].(Thr4,Gly7)-Oxytocin (1 μM, 1 min) increases spontaneous excitatory postsynaptic currents (sEPSCs) frequency in PVT neurons[1].(Thr4,Gly7)-Oxytocin (0.3 μM, 5 min) induces depolarization in both bursting cells and regular firing cells[2].(Thr4,Gly7)-Oxytocin (0.3 μM, 5 min) depolarizes subicular neurons by activating TRPV1 channels[2]. | ||||||
Name | (Thr4,Gly7)-Oxytocin | ||||||
CAS | 60786-59-6 | ||||||
Formula | C39H61N11O12S2 | ||||||
Molar Mass | 940.10 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |