| Bioactivity | (S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively. (S)-(-)-Propranolol hydrochloride the active enantiomer of propranolol and can be s used for study of hypertension, pheochromocytoma, myocardial infarction, cardiac arrhythmias, angina pectoris, and hypertrophic cardiomyopathy[2]. |
| Target | log Kd: -8.16 (β1-adrenergic receptor)log Kd: -9.08 (β2-adrenergic receptor)log Kd: -6.93 (β3-adrenergic receptor) |
| Name | (S)-(-)-Propranolol hydrochloride |
| CAS | 4199-10-4 |
| Formula | C16H22ClNO2 |
| Molar Mass | 295.80 |
| Appearance | Solid |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
| Reference | [1]. Jillian G Baker , et al. The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. Br J Pharmacol. 2005 Feb;144(3):317-22. |
(S)-(-)-Propranolol hydrochloride
CAS: 4199-10-4 F: C16H22ClNO2 W: 295.80
(S)-(-)-Propranolol hydrochloride is a β-adrenergic receptor antagonist with log Kd values of -8.16, -9.08, and -6.93
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