Bioactivity | (Arg)9 (Nona-L-arginine) TFA is a cell-penetrating peptide (CPP) made up of 9 arginine residues. (Arg)9 TFA has neuroprotective property, exhibits neuroprotective activity with an IC50 of 0.78 μM in the glutamic acid model[1][2]. | ||||||
Invitro | (Arg)9 (Nona-L-arginine; 5-10 μM) TFA provides significant neuroprotection in a dose–response manner following glutamic acid exposure (IC50=0.78 μM). Following kainic acid exposure, (Arg)9 TFA is neuroprotective, but less effective than in the glutamic acid model (IC50=0.81 μM). (Arg)9 TFA also shows neuroprotection following in vitro ischemia (IC50=6 μM)[1]. | ||||||
Name | (Arg)9 TFA | ||||||
CAS | 2283335-13-5 | ||||||
Sequence | Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg | ||||||
Shortening | RRRRRRRRR | ||||||
Formula | C56H111N36F3O12 | ||||||
Molar Mass | 1537.71 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |