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(6S)-Tetrahydrofolic acid

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Bioactivity (6S)-Tetrahydrofolic acid is 1000-fold more active than the (6R) form at promoting the binding of fluorodeoxyuridylate to thymidylate synthase and 600-fold more active as a growth factor of P. cerevisiae. (6S)-Tetrahydrofolic acid also has a low affinity and high dissociation rate for folate-binding protein[1].
CAS 71963-69-4
Formula C19H23N7O6
Molar Mass 445.43
Transport Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Steven W. Bailey, et al. Synthesis of Tetrahydropteridine C6-Stereoisomers, Including N6-Formyl-(68)-tetrahydrofolic Acid. The Journal of Organic Chemistry, 57(16), 4470-4477.

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