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(2R,3S)-Brassinazole

CAS: 259200-30-1 F: C18H18ClN3O W: 327.81

Brassinazole (0.5, 1, 5 μM) causes markedly deformed seedlings, whose morphology is similar to that of BR-deficient mut
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Bioactivity Brassinazole (0.5, 1, 5 μM) causes markedly deformed seedlings, whose morphology is similar to that of BR-deficient mutants. Brassinazole causes cress dwarfism, altering leaf morphology such as the typical downward curl and dark green appearance of Arabidopsis BR-deficient mutants. However, administration of 10 nM BR reversed dwarfism[1].
Target Brassinosteroid (BR) biosynthesis
Invitro Brassinazole (0.5, 1, 5 μM) 显着导致幼苗畸形,其形态与 BR 缺陷突变体相似。Brassinazole 会导致水芹侏儒症,改变叶片形态,例如拟南芥 BR 缺陷突变体会有的典型的向下卷曲和深绿色外观。然而,施用 10 nM BR可逆转侏儒症[1]。
Name (2R,3S)-Brassinazole
CAS 259200-30-1
Formula C18H18ClN3O
Molar Mass 327.81
Appearance Solid
Transport Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Reference [1]. Yoshida Shigeo, et al. Preparation of (1,2,4-triazolyl)alkanols as specific inhibitors of brassinosteroid biosynthesis: Japan, JP2000053657. 2000-02-22. [2]. Asami T, et al. Mode of action of brassinazole: a specific inhibitor of brassinosteroid biosynthesis[M]. 2000. [3]. T Asami, et al. Characterization of Brassinazole, a Triazole-Type Brassinosteroid Biosynthesis Inhibitor. Plant Physiol. 2000 May;123(1):93-100.