Title: Trimethidinium Methosulfate

CAS Registry Number: 14149-43-0

CAS Name: 1,3,8,8-Tetramethyl-3-[3-(trimethylammonio)propyl]-3-azoniabicyclo[3.2.1]octane bis(methyl sulfate)

Additional Names: 3-[3-(dimethylamino)propyl]-1,3,8,8-tetramethyl-3-azoniabicyclo[3.2.1]octane methyl sulfate methosulfate; 1-(3-dimethylaminopropyl)-3,4,4-trimethyl-3,5-ethylenepiperidinium methyl sulfate methosulfate; N-(g-trimethylammoniumpropyl)-N-methylcamphidinium methyl sulfate; camphidonium

Manufacturers' Codes: Wy-1395; HA-106

Trademarks: Ostensin (Wyeth)

Molecular Formula: C19H42N2O8S2

Molecular Weight: 490.68

Percent Composition: C 46.51%, H 8.63%, N 5.71%, O 26.09%, S 13.07%

Literature References: Prepd from 1-(3-dimethylaminopropyl)-3,4,4-trimethyl-3,5-ethylenepiperidine and methyl sulfate: Schmidt, DE 1086703 (1960 to Thomae), C.A. 55, 27379i (1961). Ganglion blocking agent.

Properties: Crystals, mp 192-193°.

Melting point: mp 192-193°

Therap-Cat: Antihypertensive.

Keywords: Antihypertensive; Quaternary Ammonium Compounds.

 

 

Status: This monograph has been retired and is no longer subject to revision or update.