Title: Tiaprost

CAS Registry Number: 71116-82-0

CAS Name: 7-[3,5-Dihydroxy-2-[3-hydroxy-4-(3-thienyloxy)-1-butenyl]cyclopentyl]-5-heptenoic acid

Additional Names: (15-R,S)-16-(3-thienyloxy)-w-tetranor-PGF2a

Molecular Formula: C20H28O6S

Molecular Weight: 396.50

Percent Composition: C 60.58%, H 7.12%, O 24.21%, S 8.09%

Literature References: Analog of prostaglandin F2a, q.v. Prepn: W. Bartmann et al., DE 2524955 corresp to US 4258053 (1977, 1981 both to Hoechst); eidem, Prostaglandins 17, 301 (1979). Efficacy in bovine endometritis: W. Bentele et al., Tieraerztl. Umsch. 35, 676, 678, 683 (1980). Pharmacological effects: W. v. Rechenberg et al., Blue Book for the Vet. Profession (Hoechst AG) 30, 417 (1981). Administration in cattle: R. Humble, ibid. 425.

 

Derivative Type: Tromethamine salt

Additional Names: Tiaprost trometamol

Trademarks: Iliren (Provet)

Molecular Formula: C24H39NO9S

Molecular Weight: 517.63

Percent Composition: C 55.69%, H 7.59%, N 2.71%, O 27.82%, S 6.19%

 

Therap-Cat-Vet: Luteolytic.