Title: Thioglycerol

CAS Registry Number: 96-27-5

CAS Name: 3-Mercapto-1,2-propanediol

Additional Names: a-monothioglycerol; thioglycerin

Molecular Formula: C3H8O2S

Molecular Weight: 108.16

Percent Composition: C 33.31%, H 7.46%, O 29.58%, S 29.65%

Literature References: Prepn: L. Carius, Ann. 124, 221 (1862); B. Sjöberg, Ber. 75, 13 (1942). Use in fast atom bombardment MS: C. Dass, J. Mass Spectrom. 31, 77 (1996); as antioxidant in cell culture media: M. Brielmeier et al., Nucleic Acids Res. 26, 2082 (1998).

Properties: Yellowish, very viscous, hygroscopic liquid; slight sulfidic odor. bp1 100-101°. d 1.246. nD20 1.527. Flash point, closed cup: 235°F (113°C). Slightly sol in water; miscible with alcohol. Insol in ether.

Boiling point: bp1 100-101°

Flash point: Flash point, closed cup: 235°F (113°C)

Index of refraction: nD20 1.527

Density: d 1.246

Use: Antioxidant preservative; reagent in analytical chemistry, cell culture research. Matrix substrate in fast atom bombardment mass spectrometry.