Title: Reviparin Sodium

Manufacturers' Codes: LU-47311

Trademarks: Clivarin(e) (Knoll)

Literature References: Low molecular weight heparin, prepared by controlled nitrous acid degradation of a standard heparin extracted from porcine intestinal mucosa. Mean molecular weight 3900 Da (range: 3500-4500 Da). Biochemical and pharmacological profile: W. Jeske et al., Semin. Thromb. Hemostasis 19, Suppl 1, 229 (1993). Clinical pharmacokinetics: K. Andrassy et al., Thromb. Res. 73, 95 (1994). Symposium on pharmacology and clinical efficacy in the prevention of thromboembolism and restenosis: Blood Coagulation Fibrinolysis 4, S3-S60 (1993). Clinical trial in deep-vein thrombosis: H. K. Breddin et al., N. Engl. J. Med. 344, 626 (2001).

Therap-Cat: Antithrombotic.

Keywords: Antithrombotic.