Title: Pinguinain

CAS Registry Number: 37288-97-4

Literature References: A proteolytic enzyme obtained from the juice of the fruit of Bromelia pinguin Plum. ex L., Bromeliaceae (pineapple family): Asenjo, Science 95, 48 (1942); Bloch, Messing, US 2977287 (1961 to Ethicon). Immunochemical studies: E. Toro-Goyco, I. Rodriguez-Costas, Arch. Biochem. Biophys. 175, 359 (1976). Structure studies: E. Toro-Goyco et al., Biochim. Biophys. Acta 622, 151 (1980).

Properties: Aq solns are capable of digesting necrotic tissue, but do not attack viable tissue. Optimum proteolytic activity is at pH 5.2 to 5.5 and also at pH 7.3. Inactivated at temps above 80°.