Title: Paricalcitol

CAS Registry Number: 131918-61-1

CAS Name: (1a,3b,7E,22E)-19-Nor-9,10-secoergosta-5,7,22-triene-1,3,25-triol

Additional Names: 19-nor-1a,25-dihydroxyvitamin D2

Trademarks: Zemplar (Abbott)

Molecular Formula: C27H44O3

Molecular Weight: 416.64

Percent Composition: C 77.83%, H 10.64%, O 11.52%

Literature References: Synthetic analog of vitamin D. Prepn: H. F. DeLuca et al., EP 387077; eidem, US 5587497 (1990, 1996 both to Wisconsin Alum. Res.). Series of articles on pharmacology and clinical experience in secondary hyperparathyroidism: Am. J. Kidney Dis. 32, Suppl. 2, S40-S66 (1998). Review: M. M. Goldenberg, Clin. Ther. 21, 432-441 (1999).

Therap-Cat: Antihyperparathyroid.

Keywords: Antihyperparathyroid.