Title: Nicofetamide

CAS Registry Number: 553-06-0

CAS Name: N-(1,2-Diphenylethyl)-3-pyridinecarboxamide

Additional Names: 1-nicotinylamino-1,2-diphenylethane; N-(1,2-diphenylethyl)nicotinamide

Manufacturers' Codes: C-1065

Trademarks: Lyspamin (Bracco)

Molecular Formula: C20H18N2O

Molecular Weight: 302.37

Percent Composition: C 79.44%, H 6.00%, N 9.26%, O 5.29%

Literature References: Anticholinergic. Prepn: Suter, US 2483250 (1949 to Cilag).

Properties: Needles from ethanol, mp 159°. Readily sol in 5N HCl; moderately sol in methanol, acetone, ether, benzene; slightly sol in ethanol. Practically insol in water and alkalies.

Melting point: mp 159°

Therap-Cat: Antispasmodic.

Keywords: Antispasmodic; Antimuscarinic.

 

 

Status: This monograph has been retired and is no longer subject to revision or update.