Title: Methyl p-Nitrobenzenesulfonate

CAS Registry Number: 6214-20-6

CAS Name: p-Nitrobenzenesulfonic acid methyl ester

Molecular Formula: C7H7NO5S

Molecular Weight: 217.20

Percent Composition: C 38.71%, H 3.25%, N 6.45%, O 36.83%, S 14.76%

Literature References: Reagent for selective methylation of cysteine residues in chemical modification of proteins: Nakagawa, Bender, J. Am. Chem. Soc. 91, 1566 (1969). Procedure: Heinrikson, Biochem. Biophys. Res. Commun. 41, 967 (1970). Prepd by the general method of reacting p-nitrobenzenesulfonyl chloride with alcohols. See Morgan, Cretcher, J. Am. Chem. Soc. 70, 375 (1948).

Properties: White to cream crystals, mp 93-95°.

Melting point: mp 93-95°

Use: Methylating agent.