Title: MADU
CAS Registry Number: 840-50-6
CAS Name: 2¢-Deoxy-5-(methylamino)uridine
Additional Names: 5-(methylamino)-2¢-deoxyuridine
Molecular Formula: C10H15N3O5
Molecular Weight: 257.24
Percent Composition: C 46.69%, H 5.88%, N 16.33%, O 31.10%
Literature References: Prepn: Visser et al., Biochim. Biophys. Acta 76, 463 (1963). Active in vitro against herpes infections: Nemes, Hilleman, Proc. Soc. Exp. Biol. Med. 119, 515 (1965); Shen, US 3322627 (1967 to Merck & Co.).
Properties: Crystals from ethanol + water, mp 180-182°.
Melting point: mp 180-182°
Therap-Cat: Antiviral.
Keywords: Antiviral; Purines/Pyrimidinones.
Status: This monograph has been retired and is no longer subject to revision or update.