Title: Cotinine

CAS Registry Number: 486-56-6

CAS Name: 1-Methyl-5-(3-pyridinyl)-2-pyrrolidinone

Additional Names: N-methyl-2-(3-pyridyl)-5-pyrrolidone

Molecular Formula: C10H12N2O

Molecular Weight: 176.22

Percent Composition: C 68.16%, H 6.86%, N 15.90%, O 9.08%

Literature References: Nicotine metabolite first described by Pinner, Arch. Pharm. 231, 378 (1893). Isolated from autoxidized nicotine, nicotine treated with hydrogen peroxide, from nicotine irradiated with ultraviolet light: Frankenburg, Vaitekunas, J. Am. Chem. Soc. 79, 149 (1957).

Properties: Viscous oil, bp6 210-211°. Absorption spectra: Frankenburg, Vaitekunas, loc. cit.

Boiling point: bp6 210-211°

 

Derivative Type: Fumarate

CAS Registry Number: 5695-98-7

Trademarks: Scotine (Unimed)

Molecular Formula: (C10H12N2O)2.C4H4O4

Molecular Weight: 468.50

Percent Composition: C 61.53%, H 6.02%, N 11.96%, O 20.49%

 

Therap-Cat: Antidepressant.

Keywords: Antidepressant; Pyrrolidones.