Title: Casanthranol

Trademarks: Cantralax (Ferrosan); Peristim (Mead Johnson)

Literature References: Complex mixture of the purified anthranol glycosides derived from Cascara sagrada, q.v., practically devoid of free anthraquinones. Two active fractions have been identified as casanthranol A and casanthranol B. Upon oxidative hydrolysis, casanthranol A yields emodin, while casanthranol B under similar treatment yields the aglycone, aloe-emodin, and traces of chrysophanic acid. Prepn: Lee, Berger, US 2552896 (1951 to Hoffmann-La Roche).

NOTE: Component of Peri-Colace, Casakol (Upjohn) .

Therap-Cat: Cathartic.

Keywords: Laxative/Cathartic.