Title: Acetaminosalol

CAS Registry Number: 118-57-0

CAS Name: 2-Hydroxybenzoic acid 4-(acetylamino)phenyl ester

Additional Names: p-acetamidophenyl salicylate; acetylaminophenyl salicylate; acetyl-p-aminosalol; p-acetylaminophenol salicylic acid ester; phenetsal

Trademarks: Salophen (Bayer); Phenosal

Molecular Formula: C15H13NO4

Molecular Weight: 271.27

Percent Composition: C 66.41%, H 4.83%, N 5.16%, O 23.59%

Literature References: Prepn: Brewster, J. Am. Chem. Soc. 40, 1136 (1918).

Properties: Crystals from hot ethanol, mp 187°. Practically insol in petr ether, cold water, more sol in warm water. Sol in alcohol, ether, benzene. Incompatible with alkalies and alkaline solns which dissolve it with decompn. The alkaline soln gradually becomes blue when boiled, the blue color being discharged upon continued boiling and again produced upon cooling and exposure to air.

Melting point: mp 187°

Therap-Cat: Analgesic; antipyretic; anti-inflammatory.

Therap-Cat-Vet: Analgesic; antipyretic.

Keywords: Analgesic (Non-Narcotic); Anti-inflammatory (Nonsteroidal); Salicylic Acid Derivatives; Antipyretic.