| CAS | 185032-24-0 |
| Sequence | H-Tyr-Lys-Gly-Arg-cyclo(-Glu-Tyr-Ile-Lys)-Leu-Ile-Thr-Arg-Pro-Arg-Tyr-NH2 |
| Sequence Single | YKGR-cyclo(-EYIK)LITRPRY-NH2 |
| Molecular Formula | C91H145N27O20 |
| Molecular Weight | 1937.32 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Obesity Research |
| Description | Tyr-Lys-Gly-(Cyclo(Glu26-Lys29),Pro34)-Neuropeptide Y (25-36) is a truncated and cyclized NPY analog, it specifically bound to Y1 receptors with a Ki of 16 nM. As an NPY agonist it inhibited norepinephrine-stimulated cAMP accumulation in SK-N-MC cells with an EC50 of 12 nM. |