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Tyr-Lys-Gly-(Cyclo(Glu26-Lys29),Pro34)-Neuropeptide Y (25-36)

CAS No.: 185032-24-0

Tyr-Lys-Gly-(Cyclo(Glu26-Lys29),Pro34)-Neuropeptide Y (25-36) is a truncated and cyclized NPY analog, it specifically bo
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CAS 185032-24-0
Sequence H-Tyr-Lys-Gly-Arg-cyclo(-Glu-Tyr-Ile-Lys)-Leu-Ile-Thr-Arg-Pro-Arg-Tyr-NH2
Sequence Single YKGR-cyclo(-EYIK)LITRPRY-NH2
Molecular Formula C91H145N27O20
Molecular Weight 1937.32
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Obesity Research
Description Tyr-Lys-Gly-(Cyclo(Glu26-Lys29),Pro34)-Neuropeptide Y (25-36) is a truncated and cyclized NPY analog, it specifically bound to Y1 receptors with a Ki of 16 nM. As an NPY agonist it inhibited norepinephrine-stimulated cAMP accumulation in SK-N-MC cells with an EC50 of 12 nM.