| CAS | 9063-57-4 |
| Sequence | H-Thr-Lys-Pro-Arg-OH |
| Sequence Single | TKPR |
| Molecular Formula | C21H40N8O6 |
| Molecular Weight | 500.6 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Antimicrobial & Antiviral Peptides|Cancer Research|Immunomodulating Agents |
| Description | Tuftsin is a natural immunomodulating peptide originally found as a phagocytosis-stimulating factor for polymorphonuclear leukocytes. The peptide is now known to elicit various other activities including antimicrobial, antiviral and antitumor effects in vivo. |
| References | 1. Acetylcholinesterase exhibits trypsin-like and metalloexopeptidase-like activity in cleaving a model peptide. D.H.Small et al., Neuroscience, 21, 991 (1987) 2. The immunomodulatory activity of tetra- and tripeptides of tuftsin-kentsin group. Z.Wieczorek et al., Peptides, 15, 215 (1994) 3. The chemical synthesis of the phagocytosis-stimulating tetrapeptide tuftsin (Thr-Lys-Pro-Arg) and its biological properties. K.Nishioka et al., Biochim. Biophys. Acta, 310, 230 (1973) |