| CAS | 177966-81-3 |
| Sequence | H-Arg-Lys-Asp-Val-Tyr-OH |
| Sequence Single | RKDVY |
| Molecular Formula | C30H49N9O9 |
| Molecular Weight | 679.77 |
| Synonyms | Crustacean Cardioactive Peptide (CCAP), amide |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Immunomodulating Agents |
| Description | Thymopentin (TP5) also called Crustacean Cardioactive Peptide (CCAP), amide, an active fragment of thymopoietin (TP), reduces endocrine and behavioral responses to experimental stress, possibly by lowering plasma TP (pTP) levels. Thymopentin (TP5) is a immunomodulatory peptide, it suppresses proliferation and induces differentiation in HL-60 cells. |
| References | 1. A high-molecular-mass neutral endopeptidase-24.5 from human lung. R.Zolfaghari et al., Biochem. J., 241, 129 (1987) 2. Elevated plasma thymopoietin associated with therapeutic nonresponsiveness in major depression. G.Goldstein et al., Biol. Psychiatry, 48, 65 (2000) |