(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat) Myelin Protein Fragments Catalog

CAS	122018-58-0
Sequence	H-His-Ser-Leu-Gly-Lys-Trp-Leu-Gly-His-Pro-Asp-Lys-Phe-OH
Sequence Single	HSLGKWLGHPDKF
Molecular Formula	C72H104N20O17
Molecular Weight	1521.74
Synonyms	(Ser140)-PLP (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat), (Ser140)-Lipophilin (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat)
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Application	Immunomodulating Agents\|Multiple Sclerosis
Description	(Ser140)-Myelin Proteolipid Protein (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat) also called (Ser140)-PLP (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat), (Ser140)-Lipophilin (139-151) (depalmitoylated) (human, bovine, dog, mouse, rat), is fragment of myelin proteolipid protein, it is an encephalitogenic determinant, able to bind to diverse sets of T cell receptors.
References	1. Epidermal growth factor suppresses nitric oxide and hydrogen peroxide production by keratinocytes. Potential role for nitric oxide in the regulation of wound healing. D.E.Heck et al., J. Biol. Chem., 267, 21277 (1992) 2. Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor. H.Waldner et al., Proc. Natl. Acad. Sci. USA, 97, 3412 (2000) 3. Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice. V.K.Tuohy et al., J. Immunol., 142, 1523 (1989)

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