CAS | 81156-93-6 |
Sequence | H-Arg-Arg-Leu-Ile-Glu-Asp-Ala-Glu-Tyr-Ala-Ala-Arg-Gly-OH |
Sequence Single | RRLIEDAEYAARG |
Molecular Formula | C64H106N22O21 |
Molecular Weight | 1519.68 |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Application | Growth Factors|Protein-Tyrosine Kinases|Virology |
Description | RR-SRC is a peptide based on the sequence surrounding the tyrosine phosphorylation site in the Rous sarcoma virus-encoded transforming protein pp60 src. In vitro tyrosine phosphorylation of the peptide is stimulated by epidermal growth factor. Furthermore, it has also been used as a substrate to monitor the purification of the insulin receptor, a protein tyrosine kinase. RR-SRC is a substrate for src-tyrosine-specific protein kinase. |
References | 1. Modulation of the effector functions of cytolytic T-lymphocytes with synthetic peptide inhibitors of protein kinases. Taffs RE, et al. J Pharm Sci. 1992 Jan;81(1):37-44. |