| CAS | 791068-69-4 |
| Sequence | H-Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DABCYL)-Arg-OH |
| Sequence Single | RE(EDANS)IHPFHLVIHTK(DABCYL)R |
| Molecular Formula | C109H157N31O22S2 |
| Molecular Weight | 2317.78 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cardiovascular System & Diseases |
| Description | Renin Substrate 1 is FRET substrate for renin with the sequence of H-Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DABCYL)-Arg-OH. Excitation at 340 nm, emission at 490 nm. |
| References | 1. Rat-proinsulin C-peptides. Amino-acid sequences. J.Markussen and F.Sundby, Eur. J. Biochem., 25, 153 (1972) 2. Inhibition of Candida albicans secreted aspartic protease by a novel series of peptidomimetics, also active on the HIV-1 protease. D.Skrbec and D.Romeo, Biochem. Biophys. Res. Commun., 297, 1350 (2002) 3. Highly sensitive intramolecularly quenched fluorogenic substrates for renin based on the combination of L-2-amino-3-(7-methoxy-4-coumaryl)propionic acid with 2,4-dinitrophenyl groups at various positions. Paschalidou K, et al. Biochem J. 2004 Sep 15;382(Pt 3):1031-8. |