| CAS | 121545-65-1 |
| Sequence | H-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-OH |
| Sequence Single | RFARKGALRQKNV |
| Molecular Formula | C67H118N26O16 |
| Molecular Weight | 1543.84 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate peptide for testing the protein kinase C activity. Protein kinase C (PKC) is involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins. |
| References | 1. The extended protein kinase C superfamily. Mellor H, et al. Biochem J. 1998 Jun 1;332 ( Pt 2):281-92. 2. Protein kinase C and lipid signaling for sustained cellular responses" (abstract). Nishizuka Y (1995). FASEB J. 9 (7): 484–96. |