| CAS | 341519-04-8 |
| Sequence | H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-Me-Lys-Thr-Cys-2-Nal-NH2 (Disulfide bond) |
| Sequence Single | p-Chloro-Fc-β-(3-pyridyl)-AW-N-Me-KTC-2-Nal-NH2 |
| Molecular Formula | C58H69ClN12O9S2 |
| Molecular Weight | 1177.85 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | PRL-3195 is a somatostatin-14 analog with the sequence of H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-N-Me-Lys-Thr-Cys-2-Nal-NH2 (Disulfide bond), it had a high affinity of 5.98 nM for the somatostatin receptor subtype 5 (sst5) (compared to 1.4 nM for somatostatin-14). Therefore, PRL3195 represents the first antagonist with high affinity for sst5. |
| References | 1. Anisylazoformylarginine: a superior assay substrate for carboxypeptidase B type enzymes. W.L.Mock and D.J.Stanford, Bioorg. Med. Chem. Lett., 12, 1193 (2002) |