CAS | 149299-77-4 |
Sequence | H-Thr-Ser-Thr-Glu-Pro-Gln-Tyr(PO3H2)-Gln-Pro-Gly-Glu-Asn-Leu-OH |
Sequence Single | TSTEPQ(p)YQPGENL |
Molecular Formula | C62H95N16O28P |
Molecular Weight | 1543.5 |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Application | Protein-Tyrosine Kinases |
Description | pp60 c-src (521-533) (phosphorylated) is the pp60 c-src carboxy-terminal phosphoregulatory peptide phosphorylated at Tyr527. pp60 c-src (521-533) (phosphorylated) is involved in the regulation of kinase activity by binding intramolecularly or intermolecularly to the SH2 domain of the pp60 c-src protein. |
References | 1. Calcium . calmodulin-dependent protein kinase II and calcium . phospholipid-dependent protein kinase activities in rat tissues assayed with a synthetic peptide. Y.Hashimoto and T.R.Soderling, Arch. Biochem. Biophys., 252, 418 (1987) 2. Detection of the site of phosphorylation in a peptide using Raman spectroscopy and partial least squares discriminant analysis. Zhang D, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2005 Jan 14;61(3):471-5. |