PeptideDB

Peptide YY (human)

CAS No.: 118997-30-1

Peptide YY (human) also called PYY (human), is a gut hormone that regulates appetite and inhibits pancreatic secretion.
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CAS 118997-30-1
Sequence H-Tyr-Pro-Ile-Lys-Pro-Glu-Ala-Pro-Gly-Glu-Asp-Ala-Ser-Pro-Glu-Glu-Leu-Asn-Arg-Tyr-Tyr-Ala-Ser-Leu-Arg-His-Tyr-Leu-Asn-Leu-Val-Thr-Arg-Gln-Arg-Tyr-NH2
Sequence Single YPIKPEAPGEDASPEELNRYYASLRHYLNLVTRQRY-NH2
Molecular Formula C194H295N55O57
Molecular Weight 4309.81
Synonyms PYY (human)
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Gastrointestinal Research
Description Peptide YY (human) also called PYY (human), is a gut hormone that regulates appetite and inhibits pancreatic secretion. Peptide YY (human) can mediate its effects through the Neuropeptide Y receptors.
References 1.  Biologically active synthetic peptides as probes of embryonic development: a competitive peptide inhibitor of fibronectin function inhibits gastrulation in amphibian embryos and neural crest cell migration in avian embryos. J.-C.Boucaut et al., J. Cell Biol., 99, 1822 (1984) 2.  The gut hormone peptide YY regulates appetite. Peptide YY, et al. Ann N Y Acad Sci. 2003 Jun;994:162-8. 3.  Isolation and characterization of peptide YY (PYY ), a candidate gut hormone that inhibits pancreatic exocrine secretion. Tatemoto K, et al. Proc Natl Acad Sci U S A. 1982 Apr;79(8):2514-8. 4.  Role of Peptide YY in blood vessel function and atherosclerosis in a rabbit model. Smith RM, et al. Clin Exp Pharmacol Physiol. 2015 Jun;42(6):648-52.