PeptideDB

pep4c

CAS No.: 243843-43-8

pep4c is an inactive control peptide analog of pep2m, a peptide inhibitor of the interaction between the C-terminus of t
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CAS 243843-43-8
Sequence H-Lys-Arg-Met-Lys-Val-Ala-Lys-Ser-Ala-Gln-OH
Sequence Single KRMKVAKSAQ
Molecular Formula C48H91N17O13S
Molecular Weight 1146.42
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Description pep4c is an inactive control peptide analog of pep2m, a peptide inhibitor of the interaction between the C-terminus of the GluA2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF).
References 1.  Functional roles of protein interactions with AMPA and kainate receptors. Collingridge and Isaac (2003). Neurosci.Res. 47 3 PMID: 12941441 2.  Role of AMPA receptor cycling in synaptic transmission and plasticity. Luscher et al (1999). Neuron 24 649 PMID: 10595516 3.  Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction. Luthi et al (1999). Neuron 24 389 PMID: 10571232 4.  NSF binding to GluR2 regulates synaptic transmission. Nishimune et al (1998). Neuron 21 87 PMID: 9697854 5.  Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism. Noel et al (1999). Neuron 23 365 PMID: 10399941