| CAS | 1872435-09-0 |
| Sequence | H-Thr-Phe-Arg-Gly-Ala-Pro-NH2 |
| Sequence Single | TFRGAP-NH2 |
| Molecular Formula | C29H46N10O7 |
| Molecular Weight | 646.75 |
| Synonyms | TFRGAPamide, Proteinase Activated Receptor 3 (1-6) amide (human), Thrombin Receptor-Like 2 (1-6) amide (human), Coagulation Factor II Receptor-Like 2 (1-6) amide (human), TFRGAP-NH2 PAR3 Tethered Ligand (Human) / Activates PAR1 and PAR2 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Hematology |
| Description | PAR-3 (1-6) amide (human) also called TFRGAPamide, Proteinase Activated Receptor 3 (1-6) amide (human), Thrombin Receptor-Like 2 (1-6) amide (human), Coagulation Factor II Receptor-Like 2 (1-6) amide (human), TFRGAP-NH2 PAR3 Tethered Ligand (Human) / Activates PAR1 and PAR2, is a human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells. |
| References | 1. Proteinase-activated receptors differentially modulate in vitro invasion of human pancreatic adenocarcinoma PANC-1 cells in correlation with changes in the expression of CDC42 protein. Liora Segal, et al. Pancreas. 2014 Jan; 43(1): 10.1097/MPA.0b013e31829. |