| CAS | 131023-24-0 |
| Sequence | H-Val-Ala-Pro-Ser-Asp-Ser-Ile-Gln-Ala-Glu-Glu-Trp-Tyr-Phe-Gly-Lys-Ile-Thr-Arg-Arg-Glu-OH |
| Sequence Single | VAPSDSIQAEEWYFGKITRRE |
| Molecular Formula | C111H168N30O35 |
| Molecular Weight | 2482.74 |
| Synonyms | Tyr-Specific Protein Kinase Inhibitor |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Protein-Tyrosine Kinases |
| Description | p60 v-src (137-157) also called Tyr-Specific Protein Kinase Inhibitor, is a 21-residue peptide corresponding to a part of the non-catalytic domain of p60 v-src (residues 137 to 157)， it was found to inhibit the tyrosine kinase activity of p60 v-src with IC50 = 7.5 μM. |
| References | 1. A synthetic peptide corresponding to residues 137 to 157 of p60v-src inhibits tyrosine-specific protein kinases. Sato K, et al. Biochem Biophys Res Commun. 1990 Sep 28;171(3):1152-9. 2. pp60c-src increases voltage-operated calcium channel currents in vascular smooth muscle cells. Wijetunge S, et al. Biochem Biophys Res Commun. 1995 Dec 26;217(3):1039-44. |