| CAS | 155918-12-0 |
| Sequence | H-Thr-Arg-Ser-Ala-Trp-NH2 |
| Sequence Single | TRSAW-NH2 |
| Molecular Formula | C27H42N10O7 |
| Molecular Weight | 618.69 |
| Synonyms | pTH-Related Protein (107-111) amide (human, bovine, dog, horse, mouse, rabbit, rat), pTH-rP (107-111) amide (human, bovine, dog, horse, mouse, rabbit, rat), Hypercalcemia of Malignancy Factor (107-111) amide (human, bovine, dog, horse, mouse, rabbit, rat) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Description | Osteostatin (1-5) amide (human, bovine, dog, horse, mouse, rabbit, rat) also called pTH-Related Protein (107-111) amide (human, bovine, dog, horse, mouse, rabbit, rat), pTH-rP (107-111) amide (human, bovine, dog, horse, mouse, rabbit, rat), Hypercalcemia of Malignancy Factor (107-111) amide (human, bovine, dog, horse, mouse, rabbit, rat), is a pTHrP fragment, it stimulated membrane-associated protein kinase C in freshly isolated rat spleen lymphocytes and thus raises the possibility of being a physiological regulator of the proliferation and other activities of lymphocytes. |
| References | 1. A heparin-binding domain in the amyloid protein precursor of Alzheimer’s disease is involved in the regulation of neurite outgrowth. D.H.Small et al., J. Neurosci., 14, 2117 (1994) 2. C-terminal fragments of parathyroid hormone-related protein, PTHrP-(107-111) and (107-139), and the N-terminal PTHrP-(1-40) fragment stimulate membrane-associated protein kinase C activity in rat spleen lymphocytes. J.F.Whitfield et al., J. Cell. Physiol., 158, 518 (1994) |