Neuropeptide Y (13-36) (porcine) Neuropeptide Y Catalog

CAS	113662-54-7
Sequence	H-Pro-Ala-Glu-Asp-Leu-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
Sequence Single	PAEDLARYYSALRHYINLITRQRY-NH2
Molecular Formula	C135H209N41O36
Molecular Weight	2982.4
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Application	Obesity Research
Description	Neuropeptide Y (13-36) (porcine) is able to compete with the intact NPY for essentially all binding sites in rat brain. However, it is less potent than the native peptide in its NPY-receptor binding affinity.
References	1. Inhibition of platelet adhesion to fibrin(ogen) in flowing whole blood by Arg-Gly-Asp and fibrinogen gamma-chain carboxy terminal peptides. R.R.Hantgan et al., Thromb. Haemost., 68, 694 (1992) 2. Centrally truncated and stabilized porcine neuropeptide Y analogs: design, synthesis, and mouse brain receptor binding. J.L.Krstenansky et al., Proc. Natl. Acad. Sci. USA, 86, 4377 (1989) 3. 125I-neuropeptide Y and 125I-peptide YY bind to multiple receptor sites in rat brain. M.W.Walker and R.J.Miller, Mol. Pharmacol., 34, 779 (1988)

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