| CAS | 891198-38-2 |
| Sequence | Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 |
| Sequence Single | Mca-PLGLEEA-Dpa-NH2 |
| Molecular Formula | C53H70N12O20 |
| Molecular Weight | 1195.21 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Cancer Research|Inflammation Research |
| Description | Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is a highly selective MMP-12 FRET substrate with a kcat/Km value of 1.85 · 10⁵ M-1s-1. Poor substrate of other MMPs with the exception of MMP-13 (kcat/Km = 0.53 · 10 ⁵ M-1s-1) and MMP-9 (0.33 · 10⁵ M-1s-1). |
| References | 1. Autocatalytic processing of site-1 protease removes propeptide and permits cleavage of sterol regulatory element-binding proteins. P.J.Espenshade et al., J. Biol. Chem., 274, 22795 (1999) |
Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2
CAS No.: 891198-38-2
Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 is a highly selective MMP-12 FRET substrate with a kcat/Km value of 1.85 ·
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