| CAS | 256394-92-0 |
| Sequence | Mca-Pro-Leu-Ala-Nva-Dap(Dnp)-Ala-Arg-NH2 |
| Sequence Single | Mca-PLA-Nva-Dpa-AR-NH2 |
| Molecular Formula | C49H68N14O15 |
| Molecular Weight | 1093.16 |
| Synonyms | MMP-2 Substrate, Fluorogenic |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Inflammation Research |
| Description | Mca-Pro-Leu-Ala-Nva-Dap(Dnp)-Ala-Arg-NH2 also called MMP-2 Substrate, Fluorogenic. Among the fluorescent peptide substrates analyzed, the FRET substrate Mca-Pro-Leu-Ala-Nva-Dpa-Ala-Arg-NH2 displayed the highest specificity constant with MMP-26 (kcat/Km = 3.0 · 10⁴ M-1s-1, pH 7.5, T = 25 °C). The fluorescence was measured at an excitation wavelength of 328 nm and emission wavelength of 393 nm. |
| References | 1. Peptide substrate specificities and protein cleavage sites of human endometase/matrilysin-2/matrix metalloproteinase-26. Hyun I Park, et al. J Biol Chem |
Mca-Pro-Leu-Ala-Nva-Dap(Dnp)-Ala-Arg-NH2
CAS No.: 256394-92-0
Mca-Pro-Leu-Ala-Nva-Dap(Dnp)-Ala-Arg-NH2 also called MMP-2 Substrate, Fluorogenic. Among the fluorescent peptide substra
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