| CAS | 50-57-7 |
| Sequence | H-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 (Disulfide bond) |
| Sequence Single | CYFQNCPKG-NH2 |
| Molecular Formula | C46H65N13O12S2 |
| Molecular Weight | 1056.23 |
| Synonyms | Lypressin, LVP, Terlipressin (4-12) |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Veterinary Medicine |
| Description | (Lys8)-Vasopressin also called Lypressin, LVP, Terlipressin (4-12), is a compound with reduced vasopressor and antidiuretic activity, as compared to AVP. (Lys8)-Vasopressin is antidiuretic hormone that have been found in pigs and some marsupial families. (Lys8)-Vasopressin induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase. |
| References | 1. Synthetic hexapeptide substrates and inhibitors of 3’:5’-cyclic AMP-dependent protein kinase. B.E.Kemp et al., Proc. Natl. Acad. Sci. USA, 73, 1038 (1976) 2. Molecular cloning and functional characterization of V2 [8-lysine] vasopressin and oxytocin receptors from a pig kidney cell line. Gorbulev V et al. Eur J Biochem. 1993 Jul 1;215(1):1-7. 3. [Arg8]vasopressin-induced contractions of rabbit urinary bladder smooth muscle. Crankshaw D et al. Eur J Pharmacol. 1989 Dec 7;173(2-3):183-8. |