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LHRH (salmon)

CAS No.: 86073-88-3

LHRH (salmon) also called LH-RH, salmon, showed a twofold greater affinity for the placental GnRH receptor than its mamm
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CAS 86073-88-3
Sequence Pyr-His-Trp-Ser-Tyr-Gly-Trp-Leu-Pro-Gly-NH2
Sequence Single pEHWSYGWLPG-NH2
Molecular Formula C60H73N15O13
Molecular Weight 1212.33
Synonyms LH-RH, salmon
Technology Synthetic
Storage -20°C, avoid light, cool and dry place
Application Pituitary & Hypothalamic Hormones|Veterinary Medicine
Description LHRH (salmon) also called LH-RH, salmon, showed a twofold greater affinity for the placental GnRH receptor than its mammalian analog. It is the hypophysiotropic decapeptide synthesized in the hypothalamus that plays a crucial role in the control of reproductive functions.
References 1.  Novel C-terminally amidated opioid peptide in human phaeochromocytoma tumour. H.Matsuo et al., Nature, 305, 721 (1983) 2.  Salmon GnRH and its analogues bind the human placental receptor. T.M.Siler-Khodr and M.Grayson, J. Soc. Gynecol. Invest., 8, 233 (2001) 3.  Inhibitory activity of luteinizing hormone-releasing hormone on tumor growth and progression. Moretti RM, et al. Endocr Relat Cancer. 2003 Jun;10(2):161-7.