CAS | 141677-18-1 |
Sequence | H-Leu-Leu-Phe-Gly-Tyr-Pro-Val-Tyr-Val-OH |
Sequence Single | LLFGYPVYV |
Molecular Formula | C56H79N9O12 |
Molecular Weight | 1070.3 |
Synonyms | HTLV-1 X-Lor Protein (16-24) (strains ATK, Caribbean), HTLV-1 PX Protein (16-24) (strains ATK, Caribbean), X-Lor Protein (16-24) (Human T-Cell Leukemia Virus Type I) (strains ATK, Caribbean), PX Protein (16-24) (Human T-Cell Leukemia Virus Type I) |
Technology | Synthetic |
Storage | -20°C, avoid light, cool and dry place |
Application | Antigen-presenting Cells|Virology |
Description | HTLV-1 Tax (11-19) also called HTLV-1 X-Lor Protein (16-24) (strains ATK, Caribbean), HTLV-1 PX Protein (16-24) (strains ATK, Caribbean), X-Lor Protein (16-24) (Human T-Cell Leukemia Virus Type I) (strains ATK, Caribbean), PX Protein (16-24) (Human T-Cell Leukemia Virus Type I) (strains ATK, Caribbean), HTLV-1 Trans-Activating Transcriptional Regulatory Protein (16-24) (strains ATK, Caribbean), is an immunodominant HLA-A2-restricted epitope. It is recognized by a high number of CD8+ cytotoxic T lymphocytes (CTLs) in patients with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), a demyelinating inflammatory neurologic disease associated with HTLV-1 infection. |