Hemopressin (human, bovine, porcine) Various Peptides Catalog

CAS	1314035-51-2
Sequence	H-Pro-Val-Asn-Phe-Lys-Leu-Leu-Ser-His-OH
Sequence Single	PVNFKLLSH
Molecular Formula	C50H79N13O12
Molecular Weight	1054.26
Technology	Synthetic
Storage	-20°C, avoid light, cool and dry place
Description	Hemopressin (human, bovine, porcine) is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin (human, bovine, porcine) is orally active, selective and inverse agonist of CB1 cannabinoid receptors. Hemopressin exerts antinociceptive action in inflammatory pain models.
References	1. Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme. Rioli et al (2003). J.Biol.Chem. 278 8547 PMID: 12500972 2. Hypotensive effects of hemopressin and bradykinin in rabbits, rats and mice. A comparative study. Blais et al (2005). Peptides 26 1317 PMID: 16042973 3. The peptide hemopressin acts through CB1 cannabinoid receptors to reduce food intake in rats and mice. Garron T Dodd, et al. J Neurosci. 2010 May 26;30(21):7369-76. 4. Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats. Elaine F Toniolo, et al. Peptides. 2014 Jun;56:125-31.

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