| CAS | 14517-43-2 |
| Sequence | H-Met-Ser-OH |
| Sequence Single | MS |
| Molecular Formula | C8H16N2O4S |
| Molecular Weight | 236.29 |
| Technology | Synthetic |
| Storage | -20°C, avoid light, cool and dry place |
| Application | Di- and Tripeptides |
| Description | H-Met-Ser-OH is a methionine- and serine-containing dipeptide. H-Met-Ser-OH binds to and translocation via intestinal di/tri-peptide transporter 1 (hPEPT1) with a Km value of 0.2 mM. H-Met-Ser-OH inhibits ACE enzyme activity. H-Met-Ser-OH can be used in the research of hypension. |
| References | 1. Affinity and translocation relationships via hPEPT1 of H-X aa-Ser-OH dipeptides: evaluation of H-Phe-Ser-OH as a pro-moiety for ibuprofen and benzoic acid prodrugs. Diana Højmark Omkvist, et al. Eur J Pharm Biopharm. 2011 Feb;77(2):327-31. 2. Application of sulfur dipeptide for preparing antihypertensive drug or health care product. Pan Wuguang, et al. Patent WO2019006954. |